GALNS Antikörper (AA 353-522)
Kurzübersicht für GALNS Antikörper (AA 353-522) (ABIN6140937)
Target
Alle GALNS Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 353-522
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Sequenz
- AGLTPPSDRA IDGLNLLPTL LQGRLMDRPI FYYRGDTLMA ATLGQHKAHF WTWTNSWENF RQGIDFCPGQ NVSGVTTHNL EDHTKLPLIF HLGRDPGERF PLSFASAEYQ EALSRITSVV QQHQEALVPA QPQLNVCNWA VMNWAPPGCE KLGKCLTPPE SIPKKCLWSH
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 353-522 of human GALNS (NP_000503.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- GALNS (Galactosamine (N-Acetyl)-6-Sulfate Sulfatase (GALNS))
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Andere Bezeichnung
- GALNS
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Hintergrund
- This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.,GALNS,GALNAC6S,GAS,GalN6S,MPS4A,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Extracellular Matrix,Ubiquitin,GALNS
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Molekulargewicht
- 58 kDa
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Gen-ID
- 2588
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UniProt
- P34059
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Pathways
- Glycosaminoglycan Metabolic Process
Target
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