FTO Antikörper (AA 416-505)
Kurzübersicht für FTO Antikörper (AA 416-505) (ABIN6140795)
Target
Alle FTO Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 416-505
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Sequenz
- AVLHEVKREG LPVEQRNEIL TAILASLTAR QNLRREWHAR CQSRIARTLP ADQKPECRPY WEKDDASMPL PFDLTDIVSE LRGQLLEAKP
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 416-505 of human FTO (NP_001073901.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- FTO (Fat Mass and Obesity-Associated (FTO))
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Andere Bezeichnung
- FTO
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Hintergrund
- This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.,FTO,ALKBH9,BMIQ14,GDFD,Epigenetics & Nuclear Signaling,Cancer,Endocrine & Metabolism,Lipid Metabolism,Endocrine and metabolic diseases,Diabetes,Metabolic disorders,Obesity,Neuroscience,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,FTO
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Molekulargewicht
- 6 kDa/12 kDa/14 kDa/58 kDa
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Gen-ID
- 79068
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UniProt
- Q9C0B1
Target
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