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FGD4 Antikörper (AA 99-198)

This anti-FGD4 antibody (ABIN6140588) is a Rabbit Polyclonal antibody detecting FGD4 in WB. Suitable for Human.
Produktnummer ABIN6140588

Quick Overview for FGD4 Antikörper (AA 99-198) (ABIN6140588)

Target

Alle FGD4 Antikörper anzeigen
FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

Reaktivität

  • 18
  • 2
  • 2
Human

Wirt

  • 18
Kaninchen

Klonalität

  • 18
Polyklonal

Konjugat

  • 13
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser FGD4 Antikörper ist unkonjugiert

Applikation

  • 17
  • 8
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • Bindungsspezifität

    • 8
    • 3
    • 2
    • 2
    • 1
    AA 99-198

    Sequenz

    QMECEEEKAA TLSSDTSIQA SEPLLDTHIV NGERDETATA PASPTTDSCD GNASDSSYRT PGIGPVLPLE ERGAETETKV QERENGESPL ELEQLDQHHE

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    FGD4 (FYVE, RhoGEF and PH Domain Containing 4 (FGD4))

    Andere Bezeichnung

    FGD4

    Hintergrund

    This gene encodes a protein that is involved in the regulation of the actin cytoskeleton and cell shape. This protein contains an actin filament-binding domain, which together with its Dbl homology domain and one of its pleckstrin homology domains, can form microspikes. This protein can activate MAPK8 independently of the actin filament-binding domain, and it is also involved in the activation of CDC42 via the exchange of bound GDP for free GTP. The activation of CDC42 also enables this protein to play a role in mediating the cellular invasion of Cryptosporidium parvum, an intracellular parasite that infects the gastrointestinal tract. Mutations in this gene can cause Charcot-Marie-Tooth disease type 4H (CMT4H), a disorder of the peripheral nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,FGD4,CMT4H,FRABP,ZFYVE6,FYVE,FGD4

    Molekulargewicht

    20 kDa/32 kDa/86 kDa

    Gen-ID

    121512

    UniProt

    Q96M96

    Pathways

    Neurotrophin Signalübertragung
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