FAM173B Antikörper (AA 1-233)

Produktnummer ABIN6140451

Produktdetails anti-FAM173B Antikörper

Target: FAM173B (Family with Sequence Similarity 173, Member B (FAM173B))

Bindungsspezifität: AA 1-233

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM173B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: MEGGGGIPLE TLKEESQSRH VLPASFEVNS LQKSNWGFLL TGLVGGTLVA VYAVATPFVT PALRKVCLPF VPATTKQIEN VVKMLRCRRG SLVDIGSGDG RIVIAAAKKG FTAVGYELNP WLVWYSRYRA WREGVHGSAK FYISDLWKVT FSQYSNVVIF GVPQMMLQLE KKLERELEDD ARVIACRFPF PHWTPDHVTG EGIDTVWAYD ASTFRGREKR PCTSMHFQLP IQA

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human FAM173B (NP_954584.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu FAM173B

Target: FAM173B (Family with Sequence Similarity 173, Member B (FAM173B))

Andere Bezeichnung: FAM173B (FAM173B Produkte)

Synonyme: RGD1560629 antikoerper, JS-2 antikoerper, A930016P21Rik antikoerper, AA987072 antikoerper, family with sequence similarity 173, member B antikoerper, family with sequence similarity 173 member B antikoerper, family with sequence similarity 173 member B S homeolog antikoerper, Fam173b antikoerper, FAM173B antikoerper, fam173b.S antikoerper

Hintergrund: Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration. Promotes chronic pain. Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS and on the engagement of spinal cord microglia.,FAM173B,JS-2,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,FAM173B

Molekulargewicht: 24 kDa/26 kDa

Gen-ID: 134145

UniProt: Q6P4H8