EWSR1 Antikörper (AA 1-300)

Produktnummer ABIN6140352

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EWSR1 in IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EWSR1 Antikörper (AA 1-300) (ABIN6140352)

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EWSR1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Produktdetails anti-EWSR1 Antikörper

Bindungsspezifität: AA 1-300

Sequenz: MASTDYSTYS QAAAQQGYSA YTAQPTQGYA QTTQAYGQQS YGTYGQPTDV SYTQAQTTAT YGQTAYATSY GQPPTGYTTP TAPQAYSQPV QGYGTGAYDT TTATVTTTQA SYAAQSAYGT QPAYPAYGQQ PAATAPTRPQ DGNKPTETSQ PQSSTGGYNQ PSLGYGQSNY SYPQVPGSYP MQPVTAPPSY PPTSYSSTQP TSYDQSSYSQ QNTYGQPSSY GQQSSYGQQS SYGQQPPTSY PPQTGSYSQA PSQYSQQSSS YGQQSSFRQD HPSSMGVYGQ ESGGFSGPGE NRSMSGPDNR

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human EWSR1 (NP_001156757.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu EWSR1

Target: EWSR1 (Ewing Sarcoma Breakpoint Region 1 (EWSR1))

Andere Bezeichnung: EWSR1

Hintergrund: This gene encodes a multifunctional protein that is involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11,22)(q24,q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.,EWSR1,EWS,EWS-FLI1,bK984G1.4,Epigenetics & Nuclear Signaling,Transcription Factors,RNA Binding,Cancer,EWSR1

Molekulargewicht: 37 kDa/61 kDa/62 kDa/68 kDa

Gen-ID: 2130

UniProt: Q01844