EBF1 Antikörper (C-Term)
Kurzübersicht für EBF1 Antikörper (C-Term) (ABIN6139908)
Target
Alle EBF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- C-Term
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Sequenz
- GGSPTFLNGS AANSPYAIVP SSPTMASSTS LPSNCSSSSG IFSFSPANMV SAVKQKSAFA PVVRPQTSPP PTCTSTNGNS LQAISGMIVP PM
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Kreuzreaktivität
- Human
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 500 to the C-terminus of human EBF1 (NP_076870.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- EBF1 (Early B-Cell Factor 1 (EBF1))
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Andere Bezeichnung
- EBF1
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Hintergrund
- Key pioneer transcription factor of B-cell specification and commitment. Recognizes variations of the palindromic sequence 5'-ATTCCCNNGGGAATT-3'. Operates in a transcription factor network to activate B-cell-specific genes and repress genes associated with alternative cell fates. For instance, positively regulates many B-cell specific genes including BCR or CD40 while repressing genes that direct cells into alternative lineages, including GATA3 and TCF7 for the T-cell lineage. In addition to its role during lymphopoiesis, controls the thermogenic gene program in adipocytes during development and in response to environmental cold (By similarity.,EBF1,COE1,EBF,O/E-1,OLF1,Epigenetics & Nuclear Signaling,Transcription Factors,EBF1
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Molekulargewicht
- 61 kDa/64 kDa
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Gen-ID
- 1879
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UniProt
- Q9UH73
Target
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