DUSP5 Antikörper (AA 315-384)

Produktnummer ABIN6139875

Dieses Anti-DUSP5-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DUSP5 in WB. Geeignet für Human.

Kurzübersicht für DUSP5 Antikörper (AA 315-384) (ABIN6139875)

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DUSP5 Antikörper

Bindungsspezifität: AA 315-384

Sequenz: SEILPSTPNP QPPSCQGEAA GSSLIGHLQT LSPDMQGAYC TFPASVLAPV PTHSTVSELS RSPVATATSC

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 315-384 of human DUSP5 (NP_004410.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DUSP5

Target: DUSP5 (Dual Specificity Phosphatase 5 (DUSP5))

Andere Bezeichnung: DUSP5

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1, is expressed in a variety of tissues with the highest levels in pancreas and brain, and is localized in the nucleus.,DUSP5,DUSP,HVH3,Signal Transduction,DUSP5

Molekulargewicht: 42 kDa

Gen-ID: 1847

UniProt: Q16690