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DMAP1 Antikörper (AA 1-305)

Der Kaninchen Polyklonal Anti-DMAP1-Antikörper wurde für WB und IHC validiert. Er ist geeignet, DMAP1 in Proben von Human zu detektieren.
Produktnummer ABIN6139677

Kurzübersicht für DMAP1 Antikörper (AA 1-305) (ABIN6139677)

Target

Alle DMAP1 Antikörper anzeigen
DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

Reaktivität

  • 38
  • 15
  • 13
  • 10
  • 8
  • 7
  • 7
  • 6
  • 4
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
Human

Wirt

  • 31
  • 4
  • 4
Kaninchen

Klonalität

  • 33
  • 6
Polyklonal

Konjugat

  • 30
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser DMAP1 Antikörper ist unkonjugiert

Applikation

  • 29
  • 13
  • 6
  • 6
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Bindungsspezifität

    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-305

    Sequenz

    MATGADVRDI LELGGPEGDA ASGTISKKDI INPDKKKSKK SSETLTFKRP EGMHREVYAL LYSDKKDAPP LLPSDTGQGY RTVKAKLGSK KVRPWKWMPF TNPARKDGAM FFHWRRAAEE GKDYPFARFN KTVQVPVYSE QEYQLYLHDD AWTKAETDHL FDLSRRFDLR FVVIHDRYDH QQFKKRSVED LKERYYHICA KLANVRAVPG TDLKIPVFDA GHERRRKEQL ERLYNRTPEQ VAEEEYLLQE LRKIEARKKE REKRSQDLQK LITAADTTAE QRRTERKAPK KKLPQKKEAE KPAVP

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-305 of human DMAP1 (NP_061973.1).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:1000 - 1:4000,IHC,1:50 - 1:200

    Kommentare

    HIGH QUALITY

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    DMAP1 (DNA Methyltransferase 1-Associated Protein 1 (DMAP1))

    Andere Bezeichnung

    DMAP1

    Hintergrund

    This gene encodes a subunit of several, distinct complexes involved in the repression or activation of transcription. The encoded protein can independently repress transcription and is targeted to replication foci throughout S phase by interacting directly with the N-terminus of DNA methyltransferase 1. During late S phase, histone deacetylase 2 is added to this complex, providing a means to deacetylate histones in transcriptionally inactive heterochromatin following replication. The encoded protein is also a component of the nucleosome acetyltransferase of H4 complex and interacts with the transcriptional corepressor tumor susceptibility gene 101 and the pro-apoptotic death-associated protein 6, among others. Alternatively spliced transcript variants encoding the same protein have been described.,DMAP1,DNMAP1,DNMTAP1,EAF2,MEAF2,SWC4,Epigenetics & Nuclear Signaling,DMAP1

    Molekulargewicht

    52 kDa

    Gen-ID

    55929

    UniProt

    Q9NPF5
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