DCPS Antikörper (AA 1-270)

Produktnummer ABIN6139449

Dieses Anti-DCPS-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DCPS in WB. Geeignet für Human.

Kurzübersicht für DCPS Antikörper (AA 1-270) (ABIN6139449)

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCPS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-DCPS Antikörper

Bindungsspezifität: AA 1-270

Sequenz: MADAAPQLGK RKRELDVEEA HAASTEEKEA GVGNGTCAPV RLPFSGFRLQ KVLRESARDK IIFLHGKVNE ASGDGDGEDA VVILEKTPFQ VEQVAQLLTG SPELQLQFSN DIYSTYHLFP PRQLNDVKTT VVYPATEKHL QKYLRQDLRL IRETGDDYRN ITLPHLESQS LSIQWVYNIL DKKAEADRIV FENPDPSDGF VLIPDLKWNQ QQLDDLYLIA ICHRRGIRSL RDLTPEHLPL LRNILHQGQE AILQRYRMKG DHLRVYLHYL

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human DCPS (NP_054745.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:1000 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu DCPS

Target: DCPS (Decapping Enzyme, Scavenger (DCPS))

Andere Bezeichnung: DCPS

Hintergrund: Decapping scavenger enzyme that catalyzes the cleavage of a residual cap structure following the degradation of mRNAs by the 3'->5' exosome-mediated mRNA decay pathway. Hydrolyzes cap analog structures like 7-methylguanosine nucleoside triphosphate (m7GpppG with up to 10 nucleotide substrates (small capped oligoribonucleotides and specifically releases 5'-phosphorylated RNA fragments and 7-methylguanosine monophosphate (m7GMP. Cleaves cap analog structures like tri-methyl guanosine nucleoside triphosphate (m3(2,2,7GpppG with very poor efficiency. Does not hydrolyze unmethylated cap analog (GpppG and shows no decapping activity on intact m7GpppG-capped mRNA molecules longer than 25 nucleotides. Does not hydrolyze 7-methylguanosine diphosphate (m7GDP to m7GMP. May also play a role in the 5'->3 mRNA decay pathway, m7GDP, the downstream product released by the 5'->3' mRNA mediated decapping activity, may be also converted by DCPS to m7GMP. Binds to m7GpppG and strongly to m7GDP. Plays a role in first intron splicing of pre-mRNAs. Inhibits activation-induced cell death.,DCPS,ARS,DCS1,HINT-5,HINT5,HSL1,HSPC015,Epigenetics & Nuclear Signaling,DCPS

Molekulargewicht: 38 kDa

Gen-ID: 28960

UniProt: Q96C86