DAZL Antikörper (AA 186-295)
Kurzübersicht für DAZL Antikörper (AA 186-295) (ABIN6139416)
Target
Alle DAZL Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 186-295
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Sequenz
- VYNYQMPPQW PVGEQRSYVV PPAYSAVNYH CNEVDPGAEV VPNECSVHEA TPPSGNGPQK KSVDRSIQTV VSCLFNPENR LRNSVVTQDD YFKDKRVHHF RRSRAMLKSV
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 186-295 of human DAZL (NP_001342.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- DAZL (Deleted in Azoospermia-Like (DAZL))
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Andere Bezeichnung
- DAZL
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Hintergrund
- The DAZ (Deleted in AZoospermia) gene family encodes potential RNA binding proteins that are expressed in prenatal and postnatal germ cells of males and females. The protein encoded by this gene is localized to the nucleus and cytoplasm of fetal germ cells and to the cytoplasm of developing oocytes. In the testis, this protein is localized to the nucleus of spermatogonia but relocates to the cytoplasm during meiosis where it persists in spermatids and spermatozoa. Transposition and amplification of this autosomal gene during primate evolution gave rise to the DAZ gene cluster on the Y chromosome. Mutations in this gene have been linked to severe spermatogenic failure and infertility in males. Two transcript variants encoding different isoforms have been found for this gene.,DAZL,DAZH,DAZL1,DAZLA,SPGYLA,Epigenetics & Nuclear Signaling,Cell Biology & Developmental Biology,Stem Cells,Germline Stem Cells,DAZL
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Molekulargewicht
- 33 kDa/35 kDa
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Gen-ID
- 1618
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UniProt
- Q92904
Target
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