Dystroglycan Antikörper (AA 654-749)
Kurzübersicht für Dystroglycan Antikörper (AA 654-749) (ABIN6139391)
Target
Alle Dystroglycan (DAG1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 654-749
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Sequenz
- SIVVEWTNNT LPLEPCPKEQ IAGLSRRIAE DDGKPRPAFS NALEPDFKAT SITVTGSGSC RHLQFIPVVP PRRVPSEAPP TEVPDRDPEK SSEDDV
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 654-749 of human DAG1 (NP_004384.4).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000,IF,1:20 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Dystroglycan (DAG1) (Dystroglycan 1 (DAG1))
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Andere Bezeichnung
- DAG1
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Hintergrund
- This gene encodes dystroglycan, a central component of dystrophin-glycoprotein complex that links the extracellular matrix and the cytoskeleton in the skeletal muscle. The encoded preproprotein undergoes O- and N-glycosylation, and proteolytic processing to generate alpha and beta subunits. Certain mutations in this gene are known to cause distinct forms of muscular dystrophy. Alternative splicing results in multiple transcript variants, all encoding the same protein.,156DAG,A3a,AGRNR,DAG,MDDGA9,MDDGC7,MDDGC9,DAG1,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,Neuroscience,DAG1
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Molekulargewicht
- 97 kDa
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Gen-ID
- 1605
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UniProt
- Q14118
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Pathways
- Maintenance of Protein Location, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus
Target
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