CYBB Antikörper (AA 100-200)

Produktnummer ABIN6139300

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CYBB in WB. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CYBB Antikörper (AA 100-200) (ABIN6139300)

Target: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYBB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CYBB Antikörper

Bindungsspezifität: AA 100-200

Sequenz: FHKMVAWMIA LHSAIHTIAH LFNVEWCVNA RVNNSDPYSV ALSELGDRQN ESYLNFARKR IKNPEGGLYL AVTLLAGITG VVITLCLILI ITSSTKTIRR S

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human NOX2/gp91phox (NP_000388.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CYBB

Target: CYBB (Cytochrome B-245, beta Polypeptide (CYBB))

Andere Bezeichnung: CYBB

Hintergrund: Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase, neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole.,AMCBX2,CGD,GP91-1,GP91-PHOX,GP91PHOX,IMD34,NOX2,p91-PHOX,CYBB,Cancer,Endocrine & Metabolism,Immunology & Inflammation,CYBB

Molekulargewicht: 65 kDa

Gen-ID: 1536

UniProt: P04839