CYB5R3 Antikörper (AA 125-334)
Kurzübersicht für CYB5R3 Antikörper (AA 125-334) (ABIN6139298)
Target
Alle CYB5R3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 125-334
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Sequenz
- RPYTPISSDD DKGFVDLVIK VYFKDTHPKF PAGGKMSQYL ESMQIGDTIE FRGPSGLLVY QGKGKFAIRP DKKSNPIIRT VKSVGMIAGG TGITPMLQVI RAIMKDPDDH TVCHLLFANQ TEKDILLRPE LEELRNKHSA RFKLWYTLDR APEAWDYGQG FVNEEMIRDH LPPPEEEPLV LMCGPPPMIQ YACLPNLDHV GHPTERCFVF
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 125-334 of human CYB5R3 (NP_001165131.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CYB5R3 (Cytochrome B5 Reductase 3 (CYB5R3))
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Andere Bezeichnung
- CYB5R3
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Hintergrund
- This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.,CYB5R3,B5R,DIA1,Cancer,Signal Transduction,Endocrine & Metabolism,Lipid Metabolism,Cholesterol Metabolism,Drug metabolism,Cardiovascular,Lipids,CYB5R3
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Molekulargewicht
- 31 kDa/34 kDa/38 kDa
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Gen-ID
- 1727
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UniProt
- P00387
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Pathways
- SARS-CoV-2 Protein Interaktom
Target
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