Cathepsin F Antikörper (AA 270-484)

Produktnummer ABIN6139225

Produktdetails anti-Cathepsin F Antikörper

Target: Cathepsin F (CTSF)

Bindungsspezifität: AA 270-484

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cathepsin F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Sequenz: LAPPEWDWRS KGAVTKVKDQ GMCGSCWAFS VTGNVEGQWF LNQGTLLSLS EQELLDCDKM DKACMGGLPS NAYSAIKNLG GLETEDDYSY QGHMQSCNFS AEKAKVYIND SVELSQNEQK LAAWLAKRGP ISVAINAFGM QFYRHGISRP LRPLCSPWLI DHAVLLVGYG NRSDVPFWAI KNSWGTDWGE KGYYYLHRGS GACGVNTMAS SAVVD

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 270-484 of human CTSF (NP_003784.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:50 - 1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Cathepsin F

Target: Cathepsin F (CTSF)

Andere Bezeichnung: CTSF (CTSF Produkte)

Synonyme: CTSF antikoerper, MGC140519 antikoerper, cb420 antikoerper, sb:cb420 antikoerper, zgc:153093 antikoerper, LOC100101596 antikoerper, Ctsf antikoerper, ACYPI000376 antikoerper, catf antikoerper, CATSF antikoerper, CLN13 antikoerper, AI481912 antikoerper, cathepsin F antikoerper, cathepsin W antikoerper, CTSF antikoerper, ctsf antikoerper, Ctsf antikoerper, ctsw antikoerper, Tsp_02382 antikoerper

Hintergrund: Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.,CTSF,CATSF,CLN13,Immunology & Inflammation,Cell Intrinsic Innate Immunity Signaling Pathway,CTSF

Molekulargewicht: 53 kDa

Gen-ID: 8722

UniProt: Q9UBX1