CTSC Antikörper (AA 25-134)

Produktnummer ABIN6139221

Dieses Anti-CTSC-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CTSC in WB. Geeignet für Human.

Kurzübersicht für CTSC Antikörper (AA 25-134) (ABIN6139221)

Target: CTSC (Cathepsin C (CTSC))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CTSC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-CTSC Antikörper

Bindungsspezifität: AA 25-134

Sequenz: DTPANCTYLD LLGTWVFQVG SSGSQRDVNC SVMGPQEKKV VVYLQKLDTA YDDLGNSGHF TIIYNQGFEI VLNDYKWFAF FKYKEEGSKV TTYCNETMTG WVHDVLGRNW

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 25-134 of human CTSC (NP_001805.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CTSC

Target: CTSC (Cathepsin C (CTSC))

Andere Bezeichnung: CTSC

Hintergrund: This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis.,CTSC,CPPI,DPP-I,DPP1,DPPI,HMS,JP,JPD,PALS,PDON1,PLS,Cell Biology & Developmental Biology,Ubiquitin,CTSC

Molekulargewicht: 15 kDa/51 kDa

Gen-ID: 1075

UniProt: P53634