Coilin Antikörper (AA 297-576)
Kurzübersicht für Coilin Antikörper (AA 297-576) (ABIN6138829)
Target
Alle Coilin (COIL) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 297-576
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Sequenz
- KLGFSLTPSK GKTSGTTSSS SDSSAESDDQ CLMSSSTPEC AAGFLKTVGL FAGRGRPGPG LSSQTAGAAG WRRSGSNGGG QAPGASPSVS LPASLGRGWG REENLFSWKG AKGRGMRGRG RGRGHPVSCV VNRSTDNQRQ QQLNDVVKNS STIIQNPVET PKKDYSLLPL LAAAPQVGEK IAFKLLELTS SYSPDVSDYK EGRILSHNPE TQQVDIEILS SLPALREPGK FDLVYHNENG AEVVEYAVTQ ESKITVFWKE LIDPRLIIES PSNTSSTEPA
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 297-576 of human Coilin (NP_004636.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IP,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Coilin (COIL)
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Andere Bezeichnung
- COIL
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Hintergrund
- The protein encoded by this gene is an integral component of Cajal bodies (also called coiled bodies). Cajal bodies are nuclear suborganelles of varying number and composition that are involved in the post-transcriptional modification of small nuclear and small nucleolar RNAs. The N-terminus of the coilin protein directs its self-oligomerization while the C-terminus influences the number of nuclear bodies assembled per cell. Differential methylation and phosphorylation of coilin likely influences its localization among nuclear bodies and the composition and assembly of Cajal bodies. This gene has pseudogenes on chromosome 4 and chromosome 14.,COIL,CLN80,p80-coilin,coilin,Coilin,Epigenetics & Nuclear Signaling,Neuroscience,Cell Type Marker,Neuron marker,COIL
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Molekulargewicht
- 62 kDa
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Gen-ID
- 8161
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UniProt
- P38432
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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