CNOT7 Antikörper (AA 90-160)

Produktnummer ABIN6138783

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNOT7 in WB und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNOT7 Antikörper (AA 90-160) (ABIN6138783)

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-CNOT7 Antikörper

Bindungsspezifität: AA 90-160

Sequenz: PGTSTWQFNF KFNLTEDMYA QDSIELLTTS GIQFKKHEEE GIETQYFAEL LMTSGVVLCE GVKWLSFHSG Y

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 90-160 of human CNOT7 (NP_037486.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:200 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu CNOT7

Target: CNOT7 (CCR4-NOT Transcription Complex, Subunit 7 (CNOT7))

Andere Bezeichnung: CNOT7

Hintergrund: The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X.,CNOT7,CAF-1,CAF1,Caf1a,hCAF-1,Epigenetics & Nuclear Signaling,CNOT7

Molekulargewicht: 28 kDa/32 kDa

Gen-ID: 29883

UniProt: Q9UIV1

Pathways: Ribonucleoprotein Complex Subunit Organization