CIRBP Antikörper (AA 1-172)
Kurzübersicht für CIRBP Antikörper (AA 1-172) (ABIN6138628)
Target
Alle CIRBP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-172
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Sequenz
- MASDEGKLFV GGLSFDTNEQ SLEQVFSKYG QISEVVVVKD RETQRSRGFG FVTFENIDDA KDAMMAMNGK SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD RGYGGNRFES RSGGYGGSRD YYSSRSQSGG YSDRSSGGSY RDSYDSYATH NE
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-172 of human CIRBP (NP_001271.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:100,IF,1:10 - 1:100
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
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Andere Bezeichnung
- CIRBP
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Hintergrund
- Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor (By similarity. Promotes assembly of stress granules (SGs, when overexpressed.,CIRBP,CIRP,Epigenetics & Nuclear Signaling,RNA Binding,Cell Biology & Developmental Biology,Cell Cycle,CIRBP
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Molekulargewicht
- 18 kDa/26 kDa/28 kDa
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Gen-ID
- 1153
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UniProt
- Q14011
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Pathways
- Ribonucleoprotein Complex Subunit Organization
Target
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