CHRND Antikörper (AA 22-245)
Kurzübersicht für CHRND Antikörper (AA 22-245) (ABIN6138596)
Target
Alle CHRND Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 22-245
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Sequenz
- LNEEERLIRH LFQEKGYNKE LRPVAHKEES VDVALALTLS NLISLKEVEE TLTTNVWIEH GWTDNRLKWN AEEFGNISVL RLPPDMVWLP EIVLENNNDG SFQISYSCNV LVYHYGFVYW LPPAIFRSSC PISVTYFPFD WQNCSLKFSS LKYTAKEITL SLKQDAKENR TYPVEWIIID PEGFTENGEW EIVHRPARVN VDPRAPLDSP SRQDITFYLI IRRK
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 22-245 of human CHRND (NP_000742.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CHRND (Cholinergic Receptor, Nicotinic, delta (Muscle) (CHRND))
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Andere Bezeichnung
- CHRND
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Hintergrund
- The acetylcholine receptor of muscle has 5 subunits of 4 different types: 2 alpha and 1 each of beta, gamma and delta subunits. After acetylcholine binding, the receptor undergoes an extensive conformation change that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. Defects in this gene are a cause of multiple pterygium syndrome lethal type (MUPSL), congenital myasthenic syndrome slow-channel type (SCCMS), and congenital myasthenic syndrome fast-channel type (FCCMS). Several transcript variants encoding different isoforms have been found for this gene.,CHRND,ACHRD,CMS2A,CMS3A,CMS3B,CMS3C,FCCMS,SCCMS,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,CHRND
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Molekulargewicht
- 57 kDa/58 kDa
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Gen-ID
- 1144
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UniProt
- Q07001
Target
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