CD163 Antikörper (AA 750-1050)
Kurzübersicht für CD163 Antikörper (AA 750-1050) (ABIN6138118)
Target
Alle CD163 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 750-1050
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Sequenz
- LSDAHVVCRQ LGCGEAINAT GSAHFGEGTG PIWLDEMKCN GKESRIWQCH SHGWGQQNCR HKEDAGVICS EFMSLRLTSE ASREACAGRL EVFYNGAWGT VGKSSMSETT VGVVCRQLGC ADKGKINPAS LDKAMSIPMW VDNVQCPKGP DTLWQCPSSP WEKRLASPSE ETWITCDNKI RLQEGPTSCS GRVEIWHGGS WGTVCDDSWD LDDAQVVCQQ LGCGPALKAF KEAEFGQGTG PIWLNEVKCK GNESSLWDCP ARRWGHSECG HKEDAAVNCT DISVQKTPQK ATTGRSSRQS S
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 750-1050 of human CD163 (NP_004235.4).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:1000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CD163
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Andere Bezeichnung
- CD163
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Hintergrund
- The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.,CD163,M130,MM130,SCARI1,Immunology & Inflammation,CD markers,Cell Intrinsic Innate Immunity Signaling Pathway,Cardiovascular,CD163
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Molekulargewicht
- 121 kDa/124 kDa/125 kDa
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Gen-ID
- 9332
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UniProt
- Q86VB7
Target
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