CBX6 Antikörper (AA 80-180)
Kurzübersicht für CBX6 Antikörper (AA 80-180) (ABIN6138026)
Target
Alle CBX6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 80-180
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Sequenz
- LLKARAQAEA LRISDVHFSV KPSASASSPK LHSSAAVHRL KKDIRRCHRM SRRPLPRPDP QGGSPGLRPP ISPFSETVRI INRKVKPREP KRNRIILNLK V
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 80-180 of human CBX6 (NP_055107.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000,IHC,1:50 - 1:200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- CBX6 (Chromobox Homolog 6 (CBX6))
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Andere Bezeichnung
- CBX6
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Hintergrund
- Component of a Polycomb group (PcG multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Possibly contributes to the target selectivity of the PRC1 complex by binding specific regions of chromatin. Recruitment to chromatin might occur in an H3K27me3-independent fashion (By similarity. May have a PRC1-independent function in embryonic stem cells (By similarity.,CBX6,Epigenetics & Nuclear Signaling,Chromatin Remodeling,CBX6
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Molekulargewicht
- 43 kDa
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Gen-ID
- 23466
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UniProt
- O95503
Target
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