Calpain 3 Antikörper (AA 1-150)
Kurzübersicht für Calpain 3 Antikörper (AA 1-150) (ABIN6137918)
Target
Alle Calpain 3 (CAPN3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-150
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Sequenz
- MHGNKQHLQK DFFLYNASKA RSKTYINMRE VSQRFRLPPS EYVIVPSTYE PHQEGEFILR VFSEKRNLSE EVENTISVDR PVKKKKTKPI IFVSDRANSN KELGVDQESE EGKGKTSPDK QKQSPQPQPG SSDQESEEQQ QFRNIFKQIA
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Kreuzreaktivität
- Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 1-150 of human CAPN3 (NP_775111.1).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- Calpain 3 (CAPN3)
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Andere Bezeichnung
- CAPN3
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Hintergrund
- Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular protease, although its function has not been well established. This gene encodes a muscle-specific member of the calpain large subunit family that specifically binds to titin. Mutations in this gene are associated with limb-girdle muscular dystrophies type 2A. Alternate promoters and alternative splicing result in multiple transcript variants encoding different isoforms and some variants are ubiquitously expressed.,CAPN3,CANP3,CANPL3,LGMD2,LGMD2A,nCL-1,p94,calpain-3,Signal Transduction,Cell Biology & Developmental Biology,Ubiquitin,Neuroscience,Calcium Signaling,CAPN3
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Molekulargewicht
- 18 kDa/35 kDa/84 kDa/93 kDa/94 kDa
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Gen-ID
- 825
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UniProt
- P20807
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Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
Target
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