C10orf2 Antikörper (AA 385-684)
Kurzübersicht für C10orf2 Antikörper (AA 385-684) (ABIN6137715)
Target
Alle C10orf2 (C10ORF2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 385-684
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Sequenz
- EQAAGLRWSR FPDLNRILKG HRKGELTVFT GPTGSGKTTF ISEYALDLCS QGVNTLWGSF EISNVRLARV MLTQFAEGRL EDQLDKYDHW ADRFEDLPLY FMTFHGQQSI RTVIDTMQHA VYVYDICHVI IDNLQFMMGH EQLSTDRIAA QDYIIGVFRK FATDNNCHVT LVIHPRKEDD DKELQTASIF GSAKASQEAD NVLILQDRKL VTGPGKRYLQ VSKNRFDGDV GVFPLEFNKN SLTFSIPPKN KARLKKIKDD TGPVAKKPSS GKKGATTQNS EICSGQAPTP DQPDTSKRSK
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 385-684 of human C10orf2 (NP_068602.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- C10orf2 (C10ORF2) (Chromosome 10 Open Reading Frame 2 (C10ORF2))
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Andere Bezeichnung
- TWNK
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Hintergrund
- This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.,TWNK,ATXN8,C10orf2,IOSCA,MTDPS7,PEO,PEO1,PEOA3,PRLTS5,SANDO,SCA8,TWINL,Epigenetics & Nuclear Signaling,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,TWNK
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Molekulargewicht
- 60 kDa/66 kDa/77 kDa
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Gen-ID
- 56652
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UniProt
- Q96RR1
Target
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