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BMP4 Antikörper (AA 1-408)

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch BMP4 in WB, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.
Produktnummer ABIN6137600

Kurzübersicht für BMP4 Antikörper (AA 1-408) (ABIN6137600)

Target

Alle BMP4 Antikörper anzeigen
BMP4 (Bone Morphogenetic Protein 4 (BMP4))

Reaktivität

  • 72
  • 45
  • 40
  • 20
  • 16
  • 13
  • 8
  • 8
  • 7
  • 6
  • 6
  • 3
  • 3
  • 2
  • 1
Human

Wirt

  • 120
  • 25
  • 11
  • 1
  • 1
Kaninchen

Klonalität

  • 128
  • 30
Polyklonal

Konjugat

  • 87
  • 27
  • 13
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser BMP4 Antikörper ist unkonjugiert

Applikation

  • 136
  • 77
  • 58
  • 42
  • 40
  • 14
  • 13
  • 7
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
  • Bindungsspezifität

    • 12
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-408

    Sequenz

    MIPGNRMLMV VLLCQVLLGG ASHASLIPET GKKKVAEIQG HAGGRRSGQS HELLRDFEAT LLQMFGLRRR PQPSKSAVIP DYMRDLYRLQ SGEEEEEQIH STGLEYPERP ASRANTVRSF HHEEHLENIP GTSENSAFRF LFNLSSIPEN EVISSAELRL FREQVDQGPD WERGFHRINI YEVMKPPAEV VPGHLITRLL DTRLVHHNVT RWETFDVSPA VLRWTREKQP NYGLAIEVTH LHQTRTHQGQ HVRISRSLPQ GSGNWAQLRP LLVTFGHDGR GHALTRRRRA KRSPKHHSQR ARKKNKNCRR HSLYVDFSDV GWNDWIVAPP GYQAFYCHGD CPFPLADHLN STNHAIVQTL VNSVNSSIPK ACCVPTELSA ISMLYLDEYD KVVLKNYQEM VVEGCGCR

    Kreuzreaktivität

    Human, Maus, Ratte

    Produktmerkmale

    Polyclonal Antibodies

    Aufreinigung

    Affinity purification

    Immunogen

    Recombinant fusion protein containing a sequence corresponding to amino acids 1-408 of human BMP4 (NP_570912.2).

    Isotyp

    IgG
  • Applikationshinweise

    WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    BMP4 (Bone Morphogenetic Protein 4 (BMP4))

    Andere Bezeichnung

    BMP4

    Hintergrund

    This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates heart development and adipogenesis. Mutations in this gene are associated with orofacial cleft and microphthalmia in human patients. The encoded protein may also be involved in the pathology of multiple cardiovascular diseases and human cancers.,BMP4,BMP2B,BMP2B1,MCOPS6,OFC11,ZYME,Cancer,Signal Transduction,Cell Biology & Developmental Biology,Growth factor,TGF-b-Smad Signaling Pathway,Wnt/β-Catenin Signaling Pathway,ESC Pluripotency and Differentiation,Immunology & Inflammation,Cytokines,NF-kB Signaling Pathway,Stem Cells,Cardiovascular,Angiogenesis,Ligand,BMP4

    Molekulargewicht

    46 kDa

    Gen-ID

    652

    UniProt

    P12644

    Pathways

    Steroid Hormone Mediated Signaling Pathway, Regulation of Muscle Cell Differentiation, Tube Formation, Skeletal Muscle Fiber Development
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