MT-ATP6 Antikörper (C-Term)

Produktnummer ABIN6137340

Der Kaninchen Polyklonal Anti-MT-ATP6-Antikörper wurde für WB, IF und IHC validiert. Er ist geeignet, MT-ATP6 in Proben von Maus zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für MT-ATP6 Antikörper (C-Term) (ABIN6137340)

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MT-ATP6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails anti-MT-ATP6 Antikörper

Bindungsspezifität: C-Term

Sequenz: MNLSMAIPLW AGAVITGFRH KLKSSLAHFL PQGTPISLIP MLIIIETISL FIQPMALAVR LTANITAGHL LMHLIGGATL VLMNISPPTA TITFIILLLL TILEFAVALI QAYVFTLLVS LYLHDNT

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100 to the C-terminus of mouse ATP6 (NP_904333.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:100 - 1:200,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Referenzen für anti-MT-ATP6 Antikörper (ABIN6137340)

Li, Zhou, Li, Li, Long, Chen, Zhang, Li, Feng: "WITHDRAWN:Mitochondrial targeting of HIF-1α inhibits hypoxia-induced apoptosis independently of its transcriptional activity." in: Free radical biology & medicine, (2018) (PubMed).

Hu, Nie, Chen, Xie, Fan, Wang, Long, Yan, Zhong, Yan: "Leucine reduces reactive oxygen species levels via an energy metabolism switch by activation of the mTOR-HIF-1α pathway in porcine intestinal epithelial cells." in: The international journal of biochemistry & cell biology, Vol. 89, pp. 42-56, (2017) (PubMed).

Details zu MT-ATP6

Target: MT-ATP6 (Mitochondrially Encoded ATP Synthase 6 (MT-ATP6))

Andere Bezeichnung: MT-ATP6

Hintergrund: Mitochondrial membrane ATP synthase (F(1F(0 ATP synthase or Complex V produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1 - containing the extramembraneous catalytic core and F(0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Key component of the proton channel, it may play a direct role in the translocation of protons across the membrane.,MT-ATP6,ATPase6,MTATP6,ATP6,Endocrine & Metabolism,Mitochondrial metabolism,Neuroscience,Neurodegenerative Diseases,MT-ATP6

Molekulargewicht: 25 kDa

Gen-ID: 17705

UniProt: P00848

Pathways: Proton Transport, Ribonucleoside Biosynthetic Process