ATG2A Antikörper (AA 700-800)
Kurzübersicht für ATG2A Antikörper (AA 700-800) (ABIN6137252)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 700-800
-
Sequenz
- DLHGIYEDGG KPPVPCLRVS KALDPKSTGR KYFLPQVVVT VNPQSSSTQW EVAPEKGEEL ELSVESPCEL REPEPSPFSS KRTMYETEEM VIPGDPEEMR T
-
Kreuzreaktivität
- Human
-
Produktmerkmale
- Polyclonal Antibodies
-
Aufreinigung
- Affinity purification
-
Immunogen
- A synthetic peptide corresponding to a sequence within amino acids 700-800 of human ATG2A (NP_055919.2).
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB,1:500 - 1:2000
-
Kommentare
-
HIGH QUALITY
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
-
-
- ATG2A (ATG2 Autophagy Related 2 Homolog A (S. Cerevisiae) (ATG2A))
-
Andere Bezeichnung
- ATG2A
-
Hintergrund
- Lipid transfer protein involved in autophagosome assembly. Tethers the edge of the isolation membrane (IM to the endoplasmic reticulum (ER and mediates direct lipid transfer from ER to IM for IM expansion. Binds to the ER exit site (ERES, which is the membrane source for autophagosome formation, and extracts phospholipids from the membrane source and transfers them to ATG9 (ATG9A or ATG9B to the IM for membrane expansion. Lipid transfer activity is enhanced by WIPI1 and WDR45/WIPI4, which promote ATG2A-association with phosphatidylinositol 3-monophosphate (PI3P-containing membranes. Also regulates lipid droplets morphology and distribution within the cell.,ATG2A,Endocrine & Metabolism,Mitochondrial metabolism,ATG2A
-
Molekulargewicht
- 13 kDa/35 kDa/212 kDa/213 kDa
-
Gen-ID
- 23130
-
UniProt
- Q2TAZ0
Target
-