ANTXR1 Antikörper (AA 84-333)
Kurzübersicht für ANTXR1 Antikörper (AA 84-333) (ABIN6136913)
Target
Alle ANTXR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 84-333
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Sequenz
- VFSTRGTTLM KLTEDREQIR QGLEELQKVL PGGDTYMHEG FERASEQIYY ENRQGYRTAS VIIALTDGEL HEDLFFYSER EANRSRDLGA IVYCVGVKDF NETQLARIAD SKDHVFPVND GFQALQGIIH SILKKSCIEI LAAEPSTICA GESFQVVVRG NGFRHARNVD RVLCSFKIND SVTLNEKPFS VEDTYLLCPA PILKEVGMKA ALQVSMNDGL SFISSSVIIT TTHCSLHKIA SGPTTAACME
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Kreuzreaktivität
- Human, Maus
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 84-333 of human ANTXR1 (NP_060623.2).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Kommentare
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HIGH QUALITY
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- ANTXR1 (anthrax Toxin Receptor 1 (ANTXR1))
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Andere Bezeichnung
- ANTXR1
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Hintergrund
- This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.,ANTXR1,ATR,GAPO,TEM8,Cardiovascular,Angiogenesis,ANTXR1
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Molekulargewicht
- 33 kDa/37 kDa/39 kDa/41 kDa/59 kDa/62 kDa
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Gen-ID
- 84168
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UniProt
- Q9H6X2
Target
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