A1CF Antikörper (AA 50-120)

Produktnummer ABIN6136302

Der Kaninchen Polyklonal Anti-A1CF-Antikörper wurde für WB und IHC validiert. Er ist geeignet, A1CF in Proben von Human zu detektieren.

Kurzübersicht für A1CF Antikörper (AA 50-120) (ABIN6136302)

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser A1CF Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-A1CF Antikörper

Bindungsspezifität: AA 50-120

Sequenz: APPERGCEIF IGKLPRDLFE DELIPLCEKI GKIYEMRMMM DFNGNNRGYA FVTFSNKVEA KNAIKQLNNY E

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 50-120 of human A1CF (NP_055391.2).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu A1CF

Target: A1CF (APOBEC1 Complementation Factor (A1CF))

Andere Bezeichnung: A1CF

Hintergrund: Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. The gene product has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Several transcript variants encoding a few different isoforms have been found for this gene.,A1CF,ACF,ACF64,ACF65,APOBEC1CF,ASP,Epigenetics & Nuclear Signaling,A1CF

Molekulargewicht: 55 kDa/58 kDa/62 kDa/64 kDa/65 kDa

Gen-ID: 29974

UniProt: Q9NQ94