SPAG6 Antikörper (AA 180-290)

Produktnummer ABIN6133998

Dieses Anti-SPAG6-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von SPAG6 in WB. Geeignet für Human.

Kurzübersicht für SPAG6 Antikörper (AA 180-290) (ABIN6133998)

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SPAG6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SPAG6 Antikörper

Bindungsspezifität: AA 180-290

Sequenz: EIALKRIAAS ALSDIAKHSP ELAQTVVDAG AVAHLAQMIL NPDAKLKHQI LSALSQVSKH SVDLAEMVVE AEIFPVVLTC LKDKDEYVKK NASTLIREIA KHTPELSQLV V

Kreuzreaktivität: Human

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 180-290 of human SPAG6 (NP_758442.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu SPAG6

Target: SPAG6 (Sperm Associated Antigen 6 (SPAG6))

Andere Bezeichnung: SPAG6

Hintergrund: The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from an infertile man. This protein localizes to the tail of permeabilized human sperm and contains eight contiguous armadillo repeats, a motif known to mediate protein-protein interactions. Studies in mice suggest that this protein is involved in sperm flagellar motility and maintenance of the structural integrity of mature sperm. Several transcript variants encoding different isoforms have been found for this gene.,SPAG6,CT141,Repro-SA-1,pf16,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microtubules,Stem Cells,Germline Stem Cells,SPAG6

Molekulargewicht: 30 kDa/49 kDa/52 kDa/55 kDa/63 kDa

Gen-ID: 9576

UniProt: O75602