CD58 Antikörper (PE)

Produktnummer ABIN610163

Der Maus Monoklonal Anti-CD58-Antikörper wurde für FACS und Func validiert. Er ist geeignet, CD58 in Proben von Human zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für CD58 Antikörper (PE) (ABIN610163)

Target: CD58

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD58 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS), Functional Studies (Func)

Klon: TS2-9

Produktdetails anti-CD58 Antikörper (PE)

Spezifität: Both transmembrane and GPI anchored CD58.

Aufreinigung: Gel filtration

Immunogen: Human cytotoxic T cells.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: Flo, Func

Usage: Function: Inhibits HLA-DR mediated T cell cytotoxicity. The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: 50 mM sodium phosphate,  pH 7.5, 500 mM potassium chloride, 150 mM sodium chloride, 15 % Glycerol, 0.2 % BSA, 0.04 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Do not freeze. Product is photosensitive and should be protected from light.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze. Protect from light.

Referenzen für anti-CD58 Antikörper (PE) (ABIN610163)

Zeng, Si, Yu, Le, Ng, Teng, Ryan, Wang, Ponniah, Pallen: "PTP alpha regulates integrin-stimulated FAK autophosphorylation and cytoskeletal rearrangement in cell spreading and migration." in: The Journal of cell biology, Vol. 160, Issue 1, pp. 137-46, (2003) (PubMed).

Feuillet, Semichon, Restouin, Harriague, Janzen, Magee, Collette, Bismuth: "The distinct capacity of Fyn and Lck to phosphorylate Sam68 in T cells is essentially governed by SH3/SH2-catalytic domain linker interactions." in: Oncogene, Vol. 21, Issue 47, pp. 7205-13, (2002) (PubMed).

Derkinderen, Toutant, Kadaré, Ledent, Parmentier, Girault: "Dual role of Fyn in the regulation of FAK+6,7 by cannabinoids in hippocampus." in: The Journal of biological chemistry, Vol. 276, Issue 41, pp. 38289-96, (2001) (PubMed).

Kawakami, Kawakami, Aaronson, Robbins: "Acquisition of transforming properties by FYN, a normal SRC-related human gene." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 85, Issue 11, pp. 3870-4, (1988) (PubMed).

Details zu CD58

Target: CD58

Andere Bezeichnung: CD58

Hintergrund: Name/Gene ID: CD58
Family: Immunoglobulin

Synonyms: CD58, CD58 antigen, AG3, LFA-3, LFA3, Surface glycoprotein LFA-3, Surface glycoprotein lfa3, CD58 Molecule

Gen-ID: 965

UniProt: P19256