IL-17 Antikörper

Produktnummer ABIN604996

Dieses Ratte Monoklonal-Antikörper erkennt spezifisch IL-17 in WB, IHC, ELISA, FACS und IHC (p). Er zeigt eine Reaktivität gegenüber Maus.

Kurzübersicht für IL-17 Antikörper (ABIN604996)

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser IL-17 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: TC11-18H10

Produktdetails anti-IL-17 Antikörper

Marke: IHC-plus™

Spezifität: Recognizes mouse Interleukin 17, a 32kD disulfide-linked homodimer consisting of two 136 amino acid chains, which belong to the IL-17 family (classified as IL-17A to IL-17F), and signal through the IL-17 receptor (IL-17R/CDw217). IL-17 is produced primarily by activated CD4+ T cells and induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. The role of IL-17 in bone metabolism has become a focus area for studies into Rheumatoid Arthritis, in which levels of IL-17 are significantly increased and may contribute to bone destruction.

Aufreinigung: Purified from ascites.

Immunogen: E. coli-expressed, recombinant mouse IL-17A

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, IHC, IHC-P (10 μg/mL), WB

Usage: ELISA: This antibody can be used in a sandwich ELISA with LS-C41752 as a detection antibody.

Kommentare:

Target Species of Antibody: Mouse

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Borate buffered saline.

Handhabung: Minimize freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot and store at -20°C. Avoid freeze-thaw cycles.

Details zu IL-17

Target: IL-17 (IL17) (Interleukin 17 (IL17))

Andere Bezeichnung: IL17 / IL-17

Hintergrund: Name/Gene ID: IL17

Synonyms: IL17