ADAM10 Antikörper (AA 214-672) (Carboxyfluorescein (CFS))

Produktnummer ABIN602625

Produktdetails anti-ADAM10 Antikörper (Carboxyfluorescein (CFS))

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Bindungsspezifität: AA 214-672

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ADAM10 Antikörper ist konjugiert mit Carboxyfluorescein (CFS)

Applikation: Flow Cytometry (FACS)

Spezifität: Recognizes human ADAM10.

Aufreinigung: Purified

Immunogen: Recombinant human ADAM10, amino acids 214-672, UniProt accession #O14672

Type of Immunogen: Recombinant protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Approved: Flo

Usage: Suitable for use in Flow cytometry: Intracellular staining antibodies are designed for multiparameter flow cytometric analysis of cells. To stain for surface proteins (e. g. CD3, CD4, CD8) in addition to the intracellular protein, we recommend that the investigator determine whether the fixation and permeabilization steps adversely affect the surface protein. If so, surface staining of cells prior to fixation and permeabilization is recommended. For intracellular staining, cells must first be fixed and permeabilized. Use of 4 % paraformaldehyde in PBS as a fixative is recommended. Other formulations or tissue fixatives may affect the staining properties of the monoclonal antibody. For permeabilization, 0.1 % saponin in a balanced salt solution is effective in facilitating antibody entry into cells. Due to the reversible nature of cell membrane permeabilization, saponin must be included in all buffers used (i. e. both the staining and washing steps). The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 0.1 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: May be stored at 4°C for short-term only. For long-term storage and to avoid freeze-thaw cycles, aliquot and store at -20°C. Aliquots are stable for at least 1 year at -20°C.

Details zu ADAM10

Target: ADAM10 (ADAM Metallopeptidase Domain 10 (ADAM10))

Andere Bezeichnung: ADAM10 (ADAM10 Produkte)

Synonyme: ADAM10 antikoerper, Adam10 antikoerper, adam10 antikoerper, wu:fc03d12 antikoerper, ad10 antikoerper, cd156c antikoerper, kuz antikoerper, kuzbanian antikoerper, madm antikoerper, xadam10 antikoerper, ADAM-10 antikoerper, ADAM 10 antikoerper, AD10 antikoerper, CD156c antikoerper, HsT18717 antikoerper, MADM antikoerper, 1700031C13Rik antikoerper, LOC100219653 antikoerper, zgc:64203 antikoerper, ADAM metallopeptidase domain 10 antikoerper, ADAM metallopeptidase domain 10a antikoerper, ADAM metallopeptidase domain 10 S homeolog antikoerper, a disintegrin and metallopeptidase domain 10 antikoerper, ADAM metallopeptidase domain 10b antikoerper, ADAM10 antikoerper, Adam10 antikoerper, adam10a antikoerper, adam10.S antikoerper, adam10b antikoerper

Hintergrund: Name/Gene ID: ADAM10
Subfamily: Metallopeptidase M12B
Family: Protease

Synonyms: ADAM10, AD10, ADAM 10, Kuzbanian, HsT18717, CD156c, CD156c antigen, CDw156, Kuz, Kuzbanian protein homolog, MADM

Gen-ID: 102

UniProt: O14672

Pathways: Notch Signalweg, EGFR Signaling Pathway