ZFP36L1 Antikörper (Ser92)

Produktnummer ABIN5962382

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ZFP36L1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für ZFP36L1 Antikörper (Ser92) (ABIN5962382)

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ZFP36L1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-ZFP36L1 Antikörper

Bindungsspezifität: Ser92

Spezifität: Berg36,BRF1,Butyrate response factor 1,C3H1 type-like 1,cMG1,EGF-response factor 1,ERF-1,ERF1,Protein TIS11B,RNF162B,TIS11B,TISB,ZFP36L1,Zinc finger protein 36

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human TIS11B around the non-phosphorylation site of S92.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide,0.5 % BSA and 50 % glycerol  pH 7.4.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu ZFP36L1

Target: ZFP36L1 (ZFP36 Ring Finger Protein-Like 1 (ZFP36L1))

Andere Bezeichnung: TIS11B

Hintergrund: This gene is a member of the TIS11 family of early response genes, which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF. This gene is well conserved across species and has a promoter that contains motifs seen in other early-response genes. The encoded protein contains a distinguishing putative zinc finger domain with a repeating cys-his motif. This putative nuclear transcription factor most likely functions in regulating the response to growth factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.ZFP36L1 (ZFP36 Ring Finger Protein Like 1) is a Protein Coding gene. Diseases associated with ZFP36L1 include Sotos Syndrome 1. Among its related pathways are Validated targets of C-MYC transcriptional repression and PI3K / Akt Signaling. GO annotations related to this gene include poly(A) RNA binding and mRNA binding. An important paralog of this gene is ZFP36L2.

Molekulargewicht: 36kDa

Gen-ID: 677

UniProt: Q07352