GABBR1 Antikörper

Produktnummer ABIN5961044

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch GABBR1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus und Affe.

Kurzübersicht für GABBR1 Antikörper (ABIN5961044)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GABBR1 Antikörper

Spezifität: DJ271M21.1.1,dJ271M21.1.2,FLJ92613,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB R1,GABAB subunit 1c,GABABR1,GABBR1 3,GABBR1,GABR1,Gamma aminobutyric acid (GABA) B receptor 1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,GPRC3A,Seven transmembrane helix receptor

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human GABAB R1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: GABAB R1

Hintergrund: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. 

Molekulargewicht: 108kDa

Gen-ID: 2550

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process