GABBR1 Antikörper

Produktnummer ABIN5961044

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch GABBR1 in WB, ELISA und IHC (p). Er zeigt eine Reaktivität gegenüber Human, Ratte, Maus und Affe.

Kurzübersicht für GABBR1 Antikörper (ABIN5961044)

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Reaktivität: Human, Ratte, Maus, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABBR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-GABBR1 Antikörper

Spezifität: DJ271M21.1.1,dJ271M21.1.2,FLJ92613,GABA-B receptor 1,GABA-B-R1,GABA-BR1,GABAB R1,GABAB subunit 1c,GABABR1,GABBR1 3,GABBR1,GABR1,Gamma aminobutyric acid (GABA) B receptor 1,Gamma-aminobutyric acid type B receptor subunit 1,Gb1,GPRC3A,Seven transmembrane helix receptor

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the C-terminal region of human GABAB R1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu GABBR1

Target: GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))

Andere Bezeichnung: GABAB R1

Hintergrund: Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates multiple transcript variants. 

Molekulargewicht: 108kDa

Gen-ID: 2550

UniProt: Q9UBS5

Pathways: Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process