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POLR2A/RPB1 Antikörper (Ser1619)

POLR2A Reaktivität: Human, Maus, Ratte, Affe WB, IF, ELISA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5959399
  • Target Alle POLR2A/RPB1 (POLR2A) Antikörper anzeigen
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Bindungsspezifität
    • 19
    • 17
    • 11
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser1619
    Reaktivität
    • 93
    • 39
    • 38
    • 6
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte, Affe
    Wirt
    • 71
    • 22
    • 1
    • 1
    • 1
    Kaninchen
    Klonalität
    • 50
    • 46
    Polyklonal
    Konjugat
    • 65
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 1
    • 1
    Dieser POLR2A/RPB1 Antikörper ist unkonjugiert
    Applikation
    • 59
    • 30
    • 29
    • 27
    • 19
    • 10
    • 9
    • 8
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    DNA directed RNA polymerase II A,DNA-directed RNA polymerase II largest subunit RNA polymerase II 220 kd subunit,DNA-directed RNA polymerase II subunit A,DNA-directed RNA polymerase II subunit RPB1,DNA-directed RNA polymerase III largest subunit,hRPB220,hsRPB1,POLR2,Polr2a,POLRA,Polymerase (RNA) II (DNA directed) polypeptide A 220  kDa,Polymerase (RNA) II (DNA directed) polypeptide A,RNA polymerase II subunit B1,RNA-directed RNA polymerase II subunit RPB1,RPB1,RPB1,RPBh1,RpIILS,RPO2,RPOL2
    Aufreinigung
    Affinity purification
    Immunogen
    Synthesized peptide derived from human Rpb1 around the non-phosphorylation site of Ser1619.
    Isotyp
    IgG
    Top Product
    Discover our top product POLR2A Primärantikörper
  • Applikationshinweise
    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    POLR2A/RPB1 (POLR2A) (RNA Polymerase II Subunit RPB1 (POLR2A))
    Andere Bezeichnung
    Rpb1 (POLR2A Produkte)
    Hintergrund
    This gene encodes the largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a carboxy terminal domain composed of heptapeptide repeats that are essential for polymerase activity. These repeats contain serine and threonine residues that are phosphorylated in actively transcribing RNA polymerase. In addition, this subunit, in combination with several other polymerase subunits, forms the DNA binding domain of the polymerase, a groove in which the DNA template is transcribed into RNA.
    Molekulargewicht
    217kDa
    Gen-ID
    5430
    UniProt
    P24928
    Pathways
    Regulatorische RNA Pathways
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