Myosin VI Antikörper

Produktnummer ABIN5958676

Der Kaninchen Polyklonal anti-Myosin VI Antikörper (ABIN5958676) detektiert spezifisch Myosin VI in WB, ELISA und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Myosin VI Antikörper (ABIN5958676)

Target: Myosin VI (MYO6)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Myosin VI Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Myosin VI Antikörper

Spezifität: Deafness autosomal recessive 37,DFNA 22,DFNA22,DFNB 37,DFNB37,KIAA0389,MYO 6,Myo6,MYO6,Myosin VI,Myosin-VI,Myosin6,Unconventional myosin-6,Unconventional myosin-VI

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from the N-terminal region of human Myosin VI

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-300, ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Myosin VI

Target: Myosin VI (MYO6)

Andere Bezeichnung: Myosin VI

Hintergrund: This gene encodes a reverse-direction motor protein that moves toward the minus end of actin filaments and plays a role in intracellular vesicle and organelle transport. The protein consists of a motor domain containing an ATP- and an actin-binding site and a globular tail which interacts with other proteins. This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss. Alternative splicing results in multiple transcript variants encoding distinct isoforms. MYO6 (Myosin VI) is a Protein Coding gene. Diseases associated with MYO6 include Deafness, Autosomal Dominant 22 and Deafness, Autosomal Recessive 37. Among its related pathways are PAK Pathway and Vesicle-mediated transport. GO annotations related to this gene include actin binding and actin filament binding. An important paralog of this gene is MYO7A.

Molekulargewicht: 150kDa

Gen-ID: 4646

UniProt: Q9UM54

Pathways: Sensory Perception of Sound, Dicarboxylic Acid Transport, Asymmetric Protein Localization