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RYR2 Antikörper (Ser2808)

Dieses Anti-RYR2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RYR2 in ELISA, WB, IF und IHC (p). Geeignet für Human, Maus und Ratte.
Produktnummer ABIN5957596

Kurzübersicht für RYR2 Antikörper (Ser2808) (ABIN5957596)

Target

Alle RYR2 Antikörper anzeigen
RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

Reaktivität

  • 32
  • 18
  • 18
  • 3
Human, Maus, Ratte

Wirt

  • 30
  • 2
Kaninchen

Klonalität

  • 30
  • 2
Polyklonal

Konjugat

  • 21
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser RYR2 Antikörper ist unkonjugiert

Applikation

  • 15
  • 14
  • 13
  • 9
  • 5
  • 5
  • 5
  • 2
  • 2
ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • Bindungsspezifität

    • 13
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Ser2808

    Spezifität

    ARVC2,ARVD2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,hRYR-2,ryanodine receptor 2 (cardiac),Ryanodine receptor 2,RyR,RYR-2,RyR2,RYR2,Type 2 ryanodine receptor,VTSIP

    Aufreinigung

    Affinity purification

    Immunogen

    Synthesized peptide derived from human RyR-2 around the non-phosphorylation site of Ser2808.

    Isotyp

    IgG
  • Applikationshinweise

    WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Konzentration

    1 mg/mL

    Buffer

    PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C

    Informationen zur Lagerung

    Store at -20°C. Avoid freeze / thaw cycles.
  • Target

    RYR2 (Ryanodine Receptor 2 (Cardiac) (RYR2))

    Andere Bezeichnung

    RYR2

    Hintergrund

    This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.

    Molekulargewicht

    564kDa

    Gen-ID

    6262

    UniProt

    Q92736

    Pathways

    Myometrial Relaxation and Contraction
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