Dieses Anti-RYR2-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von RYR2 in ELISA, WB, IF und IHC (p). Geeignet für Human, Maus und Ratte.
RYR2
Reaktivität: Human
IHC, WB, ICC, IP
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C. Avoid freeze / thaw cycles.
Target
RYR2
(Ryanodine Receptor 2 (Cardiac) (RYR2))
Andere Bezeichnung
RYR2
Hintergrund
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia.RYR2 (Ryanodine Receptor 2) is a Protein Coding gene. Diseases associated with RYR2 include Ventricular Tachycardia, Catecholaminergic Polymorphic, 1 and Arrhythmogenic Right Ventricular Dysplasia 2. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Cell-type Dependent Selectivity of CCK2R Signaling. GO annotations related to this gene include calcium ion binding and protein kinase binding. An important paralog of this gene is RYR3.