Histone H1 Antikörper (Thr17)

Produktnummer ABIN5955952

Dieses Anti-Histone H1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Histone H1 in IF, WB, IHC (p) und ELISA. Geeignet für Human und Maus.

Kurzübersicht für Histone H1 Antikörper (Thr17) (ABIN5955952)

Target: Histone H1

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Histone H1 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF), Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA

Produktdetails anti-Histone H1 Antikörper

Bindungsspezifität: Thr17

Spezifität: HIST1H1B,H1F5,Histone H1.5,Histone H1a,Histone H1b,Histone H1s-3,HIST1H1D,H1F3,Histone H1.3,Histone H1c,Histone H1s-2,HIST1H1E,H1F4,Histone H1.4,Histone H1b,Histone H1s-4

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human Histone H1 around the non-phosphorylation site of Thr17.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol, pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Histone H1

Target: Histone H1

Hintergrund: May play a key role in the control of gene expression during oogenesis and early embryogenesis, presumably through the perturbation of chromatin structure. Essential for meiotic maturation of germinal vesicle-stage oocytes. The somatic type linker histone H1c is rapidly replaced by H1oo in a donor nucleus transplanted into an oocyte. The greater mobility of H1oo as compared to H1c may contribute to this rapid replacement and increased instability of the embryonic chromatin structure. The rapid replacement of H1c with H1oo may play an important role in nuclear remodeling.

Molekulargewicht: 23kDa

Gen-ID: 3009, 3007, 3008