TBC1D4 Antikörper (pThr642)

Produktnummer ABIN5955761

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TBC1D4 in ELISA, WB, IF und IHC (p). Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für TBC1D4 Antikörper (pThr642) (ABIN5955761)

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TBC1D4 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-TBC1D4 Antikörper

Bindungsspezifität: pThr642

Spezifität: Acrg embryonic lethality (mouse) minimal region ortholog,Acrg embryonic lethality minimal region ortholog,Acrg embryonic lethality mouse minimal region ortholog,Akt substrate of 160 kDa,AS 160,AS160,BUB2,CDC16,KIAA0603,NIDDM5,TBC (Tre 2 BUB2 CDC16) domain containing protein,TBC Tre 2 BUB2 CDC16 domain containing protein,TBC1 D4,TBC1 domain family member 4,Tbc1d4,TBCD4,Tre-2

Aufreinigung: Affinity purification

Immunogen: Synthesized peptide derived from human TBC1D4 around the phosphorylation site of Thr642

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:100-1:300, IF 1:200-1:1000, ELISA 1:5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: PBS with 0.02 % sodium azide, 0.5 % BSA and 50 % glycerol,  pH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu TBC1D4

Target: TBC1D4 (TBC1 Domain Family, Member 4 (TBC1D4))

Andere Bezeichnung: TBC1D4

Hintergrund: TBC1 domain family member 4 (TBC1D4), also designated AS160, can be insulin- and/or AKT1-induced. Insulin-stimulated phosphorylation is required for GLUT4 translocation. TBC1D4 may play a role as a GTPase activating protein for proteins in the Rab family. It is expressed primarily in skeletal muscle and heart, as well as spleen, lymph node and leukocytes. Defects in the TBC1D4 gene may cause atopic dermatitis (AD), sometimes referred to as eczema, an atopic chronic skin disease. The skin of affected individuals reacts to irritants or allergens and becomes red, flaky and itchy. The skin is also more vulnerable to inflammations, and symptoms can grow or disappear over time.

Molekulargewicht: 147kDa

Gen-ID: 9882

UniProt: O60343