Puumala Hantavirus (PUUV) Antikörper

Produktnummer ABIN5954764

Zitiert in 7+ Publikationen. Der Maus Monoklonal anti-Puumala Hantavirus Antikörper (Klon A1C5) (ABIN5954764) detektiert spezifisch Puumala Hantavirus in IHC, WB, ICC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Puumala hantavirus.

Kurzübersicht für Puumala Hantavirus (PUUV) Antikörper (ABIN5954764)

Target: Puumala Hantavirus (PUUV)

Reaktivität: Puumala hantavirus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF)

Klon: A1C5

Produktdetails

Kreuzreaktivität (Details): Puumala virus-infected cells

Produktmerkmale: The antibody is directed against the Puumala serotype nucleocapsid protein which has been shown to be the major immunogen in infections (HFRS, Nephropathia epidemica) caused by Puumala Virus. Positive cross-reaction with Sin Nombra Virus (SNV).No coss-reactivity

Aufreinigung: supernatant

Immunogen: recombinant Puumala nucleocapsid protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: contains 0.09 % sodium azide

Lagerung: RT,4 °C,-20 °C

Informationen zur Lagerung:

Storage: 4 °C,-20 °C

storageComment: short term at 2 - 8 °C, long term storage in aliquots at - 20 °C, avoid freeze/ thaw cycles

Referenzen

Gallo, Kotlik, Roingeard, Monot, Chevreux, Ulrich, Tordo, Ermonval: "Diverse susceptibilities and responses of human and rodent cells to orthohantavirus infection reveal different levels of cellular restriction." in: PLoS neglected tropical diseases, Vol. 16, Issue 10, pp. e0010844, (2022) (PubMed).

Vietzen, Hartenberger, Aberle, Puchhammer-Stöckl: "Dissection of the NKG2C NK cell response against Puumala Orthohantavirus." in: PLoS neglected tropical diseases, Vol. 15, Issue 12, pp. e0010006, (2022) (PubMed).

Hägele, Müller, Nusshag, Reiser, Zeier, Krautkrämer: "Motility of human renal cells is disturbed by infection with pathogenic hantaviruses." in: BMC infectious diseases, Vol. 18, Issue 1, pp. 645, (2019) (PubMed).

Hägele, Müller, Nusshag, Reiser, Zeier, Krautkrämer: "Virus- and cell type-specific effects in orthohantavirus infection." in: Virus research, Vol. 260, pp. 102-113, (2019) (PubMed).

Pettersson, Rasmuson, Andersson, Ahlm, Evander: "Hantavirus-specific IgA in saliva and viral antigen in the parotid gland in patients with hemorrhagic fever with renal syndrome." in: Journal of medical virology, Vol. 83, Issue 5, pp. 864-70, (2011) (PubMed).

Krautkrämer, Zeier: "Hantavirus causing hemorrhagic fever with renal syndrome enters from the apical surface and requires decay-accelerating factor (DAF/CD55)." in: Journal of virology, Vol. 82, Issue 9, pp. 4257-64, (2008) (PubMed).

Khattak, Darai, Rösen-Wolff: "Puumala virus nucleocapsid protein expressed in transgenic plants is not immunogenic after oral administration." in: Virus genes, Vol. 29, Issue 1, pp. 109-16, (2004) (PubMed).

Antigendetails

Target: Puumala Hantavirus (PUUV)

Andere Bezeichnung: Hantavirus Puumala

Substanzklasse: Virus