FH Antikörper (AA 44-510)

Produktnummer ABIN5776268

Dieses Anti-FH-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von FH in WB, ELISA, IF, FACS und ICC. Geeignet für Human.

Kurzübersicht für FH Antikörper (AA 44-510) (ABIN5776268)

Target: FH (Fumarate Hydratase (FH))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Klon: AT3F6

Produktdetails anti-FH Antikörper

Bindungsspezifität: AA 44-510

Immunogen: Recombinant human Fumarase (44-510aa) purified from E. coli

Isotyp: IgG2a kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu FH

Target: FH (Fumarate Hydratase (FH))

Andere Bezeichnung: Fumarase/FH

Hintergrund: Fumarase (Fumarate hytdratase) is an enzyme that catalyzes the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid (TCA), or Krebs cycle. This enzyme exists in both a cytosolic form and an N-terminal extended mitochondrial form. The N-terminal extended form is targeted to the mitochondrion, where the removal of the extension is the same form as in the cytoplasm. Fumarase deficiency can lead to progressive encephalopathy, cerebral atrophy and developmental delay and this enzyme also is thought to act as a tumor suppressor.

NCBI Accession: NP_000134