PGAM2 Antikörper (AA 1-253)

Produktnummer ABIN5776232

Der Maus Monoklonal anti-PGAM2 Antikörper (Klon AT5A7) (ABIN5776232) detektiert spezifisch PGAM2 in WB, IF, ELISA und ICC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PGAM2 Antikörper (AA 1-253) (ABIN5776232)

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Klon: AT5A7

Produktdetails anti-PGAM2 Antikörper

Bindungsspezifität: AA 1-253

Verwendungszweck: Human PGAM2 antibody

Aufreinigung: Purified

Immunogen: Recombinant human PGAM2 (1-253aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu PGAM2

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Andere Bezeichnung: PGAM2

Hintergrund: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Since both 3-PGA and 2-PGA are allosteric regulators of the pentose phosphate pathway (PPP) and glycine and serine synthesis pathways, respectively, PGAM2 may contribute to the biosynthesis of amino acids, 5-carbon sugar, and nucleotides precursors. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this gene cause muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease X. PGAM2 is one of two PGAM subunits found in humans and is predominantly expressed in adult muscle.

NCBI Accession: NP_000281