PGAM2 Antikörper (AA 1-253)

Produktnummer ABIN5776232

Dieses Anti-PGAM2-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von PGAM2 in WB, IF, ELISA und ICC. Geeignet für Human.

Kurzübersicht für PGAM2 Antikörper (AA 1-253) (ABIN5776232)

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGAM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunocytochemistry (ICC)

Klon: AT5A7

Produktdetails anti-PGAM2 Antikörper

Bindungsspezifität: AA 1-253

Immunogen: Recombinant human PGAM2 (1-253aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu PGAM2

Target: PGAM2 (phosphoglycerate Mutase 2 (Muscle) (PGAM2))

Andere Bezeichnung: PGAM2

Hintergrund: Phosphoglycerate mutase (PGAM) catalyzes the reversible reaction of 3-phosphoglycerate (3-PGA) to 2-phosphoglycerate (2-PGA) in the glycolytic pathway. Since both 3-PGA and 2-PGA are allosteric regulators of the pentose phosphate pathway (PPP) and glycine and serine synthesis pathways, respectively, PGAM2 may contribute to the biosynthesis of amino acids, 5-carbon sugar, and nucleotides precursors. The PGAM is a dimeric enzyme containing, in different tissues, different proportions of a slow-migrating muscle (MM) isozyme, a fast-migrating brain (BB) isozyme, and a hybrid form (MB). Mutations in this gene cause muscle phosphoglycerate mutase deficiency, also known as glycogen storage disease X. PGAM2 is one of two PGAM subunits found in humans and is predominantly expressed in adult muscle.

NCBI Accession: NP_000281