PDIA3 Antikörper (AA 25-505)

Produktnummer ABIN5776230

Dieser Maus Monoklonal Antikörper detektiert spezifisch PDIA3 in WB, ELISA, IF und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für PDIA3 Antikörper (AA 25-505) (ABIN5776230)

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PDIA3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT9E9

Produktdetails anti-PDIA3 Antikörper

Bindungsspezifität: AA 25-505

Verwendungszweck: Human GRP58/PDIA3 antibody

Aufreinigung: Purified

Immunogen: Recombinant human PDIA3 (25-505aa) purified from E. coli

Isotyp: IgG2a kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu PDIA3

Target: PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))

Andere Bezeichnung: GRP58/PDIA3

Hintergrund: PDIA3, also known as protein disulfide-isomerase A3, is a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. This protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.

NCBI Accession: NP_005304

Pathways: Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis