PDIA3 Antikörper (AA 25-505)
Kurzübersicht für PDIA3 Antikörper (AA 25-505) (ABIN5776230)
Target
Alle PDIA3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 25-505
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Verwendungszweck
- Human GRP58/PDIA3 antibody
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Aufreinigung
- Purified
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Immunogen
- Recombinant human PDIA3 (25-505aa) purified from E. coli
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Isotyp
- IgG2a kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
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- PDIA3 (Protein Disulfide Isomerase Family A, Member 3 (PDIA3))
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Andere Bezeichnung
- GRP58/PDIA3
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Hintergrund
- PDIA3, also known as protein disulfide-isomerase A3, is a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. This protein has protein disulfide isomerase activity. PDIA3 is also part of the major histocompatibility complex (MHC) class I peptide-loading complex (TAP1), which is essential for formation of the final antigen conformation and export from the endoplasmic reticulum to the cell surface.
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NCBI Accession
- NP_005304
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Pathways
- Maintenance of Protein Location, Protein targeting to Nucleus, Cell RedoxHomeostasis
Target
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