DECR1 Antikörper (AA 35-335)

Produktnummer ABIN5776166

Der Maus Monoklonal anti-DECR1 Antikörper (Klon AT3B2) (ABIN5776166) detektiert spezifisch DECR1 in WB, ELISA, ICC, IF und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DECR1 Antikörper (AA 35-335) (ABIN5776166)

Target: DECR1 (2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser DECR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: AT3B2

Produktdetails anti-DECR1 Antikörper

Bindungsspezifität: AA 35-335

Verwendungszweck: Human DECR1 antibody

Aufreinigung: Purified

Immunogen: Recombinant human DECR1 (35-335aa) purified from E. coli

Isotyp: IgG2b kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline ( pH 7.4) with 0.02 % Sodium Azide, 10 % glycerol

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing cycles

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Details zu DECR1

Target: DECR1 (2,4-Dienoyl CoA Reductase 1, Mitochondrial (DECR1))

Andere Bezeichnung: DECR1

Hintergrund: DECR1 is a mitochondrial protein that exists as a homotetramer and belongs to the family of short-chain dehydrogenases/reductases. It functions as an auxiliary enzyme of beta-oxidation andt participates in the metabolism of unsaturated fatty enoyl-CoA esters. Specifically, DECR1 uses NADP+ to catalyze the reduction of 2, 4-dienoyl-CoA to yield trans-3-enoyl-CoA, which can then be used as an intermediate in the Krebs cycle. Additionally, DECR1 is thought to function as a tumor suppressor, possibly downregulating the expression of Neu and slowing the rate of tumorigenesis.

NCBI Accession: NP_001350

Pathways: Monocarboxylic Acid Catabolic Process