NQO2 Antikörper (AA 1-231)

Produktnummer ABIN5776048

Der Maus Monoklonal Anti-NQO2-Antikörper wurde für WB, ELISA, IF und ICC validiert. Er ist geeignet, NQO2 in Proben von Human zu detektieren.

Kurzübersicht für NQO2 Antikörper (AA 1-231) (ABIN5776048)

Target: NQO2

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NQO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunocytochemistry (ICC)

Klon: AT1E3

Produktdetails anti-NQO2 Antikörper

Bindungsspezifität: AA 1-231

Immunogen: Recombinant human NQO2 (1-231aa) purified from E. coli

Isotyp: IgG1 kappa

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Lagerung: 4 °C,-20 °C,-80 °C

Informationen zur Lagerung: Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.

Details zu NQO2

Target: NQO2

Andere Bezeichnung: NQO2

Hintergrund: Quinone oxidoreductase (NQO1 and NQO2) are cytosolic proteins that catalyze metabolic redaction of quinines and derivates. NQO2 is inhibited by flavones such as quercetin. Also benzo (a) pyrene is another known inhibitor of NQO2. Even though overlapping substrates specificities have been observed for NQO1 and NQO2, such as for CB1954 activation, significant differences exist in relative affinities for the various substrates. The detoxification role of NQO2 has not been found, and it has no known endogenous biological substrates. However, NQO1 plays an important role in the detoxification of various endogenous and exogenous quinones, including estrogen quinines. Also NQO2 has a melatonin-binding site, which may explain the anti-oxidant role of melatonin related with circadian rhythm.