Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
Target
SORD
(Sorbitol Dehydrogenase (SORD))
Andere Bezeichnung
SORD
Hintergrund
SORD, also known as sorbitol dehydrogenase, is a 357 amino acid protein of the zinc-containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney, lens of the eye and malignant prostate tissue. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses. SORD deficiency may be associated with diabetic complications such as cataracts and microvascular problems.