Der Maus Monoklonal anti-OTUB1 Antikörper (Klon AT17E10) (ABIN5775962) detektiert spezifisch OTUB1 in WB, ELISA, ICC und IF.
Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Otubain 1, also known as OTUB1, is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases and inhibits cytokine gene transcription in the immune system via its interaction with an ubiquitin protease and E3 ubiquitin ligase. This protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function of polyubiquitin chain growth.