HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) Antikörper
Kurzübersicht für HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) (AA 1-242) Antikörper (ABIN5775951)
Target
Alle HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-242
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Immunogen
- Recombinant human HTATIP2 (1-242aa) purified from E. coli
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Isotyp
- IgG2a kappa
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Lagerung
- 4 °C,-20 °C,-80 °C
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Informationen zur Lagerung
- Can be stored at +2°C to +8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C. Avoid repeated freezing and thawing cycles.
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- HIV-1 Tat Interactive Protein 2, 30kDa (HTATIP2)
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Andere Bezeichnung
- TIP30/HTATIP2
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Hintergrund
- HTATIP2, also known as TIP30, is a member of the short-chain dehydrogenases/reductases (SDR) family. It acts as a tumor suppressor participating in metabolic suppression, inhibition of angiogenesis and induces the expression of apoptosis related genes Bad and Siva. HTATIP2 interacts with the activation domain of HIV-1 TAT and enhances its transcription by phosphorylating RNA polymerase II (Pol II). Defects in This protein are associated with hepatocellular carcinomas and apoptotic resistant tumor cells, suggesting a potential use for HTATIP2 in antitumor therapy.
Target
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